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Seta SetaAmazon variant predominates in 98% of COVID-19 cases in Brazil
Data July, 2021

Amazon variant predominates in 98% of COVID-19 cases in Brazil

The Gamma lineage (or P.1) shows local evolution in Brazil and is the most detected in cases of COVID-19 in the country

The most recent updates about the presence of SARS-CoV-2 in Brazil’s five regions can be monitored in real time on this map. The data is the result of scientific research by Genov, Dasa’s genome surveillance project, open to the public and aimed at monitoring COVID-19 in Brazil.

The chart bar bellow shows the behavior of the variants by state. In a left to right seeing, a timeline for the months since the beginning of the Genov project.

Context

The third Genov study, compiled from the sequencing of 956 complete genomes of SARS-CoV-2 collected in the first half of July 2021, adds relevant information about the pandemic in Brazil.

Currently, the sequencing platform is transitioning from the NextSeq equipment to the higher-capacity NovaSeq equipment, which will speed up the project. The aim is to increase the monthly number of sequenced samples to 3,000/month, which is Genov’s logistical-operational limit.

The process of analysing the genomes, of which 19 Brazilian states had at least 1 sample sequenced, with epidemiological information, clinical and laboratory data, produces new data that is vital in the fight against Covid-19 in Brazil and worldwide. The main findings of the research are shown below.

Insights

1In relation to the last study (second report - June/21), the data of July/21 is different in that it shows a drop in the frequency of the Gamma variant (P.1) and an increase in the variant derived from it: P.1.7 - in all regions of the country. Of particular note are the states of Maranhão, Tocantins and Mato Grosso do Sul where about half of the samples contained the P.1.7 variant.

2The growth of the P.1.7 sublineage (derived from the Gamma variant) may suggest an evolutionary advantage over the P.1 strain. For this reason, the report included a comparison of the viral load of samples P1.8, AY.4 and B.1.617.2.

3In the first report (May/2021), 605 of the 629 sequenced samples corresponded to the P.1 variant. In the second report (June/2021), the percentage was even higher, 1,277 of the 1,297 sequenced. However, in July/2021 (828 out of 956), the percentage dropped to a value below that of May/2021 due to an increase in the Delta variant.

4Regarding Gamma-plus variants, this study found that 14.7% (122/826) of the samples identified as Gamma corresponded to cases of the mentioned variant. This percentage represents an increase over previous reports: 2.4% of Gamma-plus cases (12/489) in the first report (May/2021) and 5.4% (67/1232) in the second (June/2021).

5The survey also identified 121 cases of the Delta variant, possibly arising from different introductions into the country. An important increase in the frequency of samples of this variant was observed in the midwest, southeast and south regions, mostly in the state of Rio de Janeiro.

6The study concludes that, at this time, the main unknown regarding the future of the pandemic in Brazil refers to the behaviour of the Delta variant. We cannot exclude the possibility of a third wave, but we cannot ignore the fact that there may be epidemiological conditions that curb the spread of Delta. The data from the next studies (August and September) will be very useful in confirming this response.

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To read the 3st Genov Report in full, click here

Read all reports click here