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Seta SetaDelta variant arrives in Brazil amid rise in cases of gamma variant
Data June, 2021

Delta variant arrives in Brazil amid rise in cases of gamma variant

The Gamma variant (P.1) continues to be the most detected in the country. The number of Gamma-Plus infections rises by 3% in a month. Outbreak that occurred among vaccinated people is being investigated

The most recent updates about the presence of SARS-CoV-2 in Brazil’s five regions can be monitored in real time on this map. The data is the result of scientific research by Genov, Dasa’s genome surveillance project, open to the public and aimed at monitoring Covid-19 in Brazil.

The chart bar bellow shows the behavior of the variants by state. In a left to right seeing, a timeline for the months since the beginning of the Genov project.

Context

The second Genov study, based on samples collected in the first half of June 2021, offers important information about the pandemic in Brazil. This report adds 127 samples collected in the 1st half of May to the 502 analysed in the 1st report, which brings the total to 629.

In addition to these, full sequencing was done on 1,297 samples, more than double compared to the first study, collected from Dasa patients who tested positive for SARS-CoV-2 in the five regions of the country. The monthly number of sequenced samples will progressively increase until it reaches 3,000/month, which is the limit of GENOV's logistic-operational capacity.

The analysis of the genomes, using epidemiological information and clinical and laboratory data, produces new knowledge that is essential in fighting Covid-19 in Brazil and worldwide. The main findings of the report are shown below.

Insights

1The report confirmed the first four Genov cases of variant 1.617.2 (Delta), three from the state of Paraná and one from Rio de Janeiro. The intention is to explore the analysis of this variant in depth when a more significant number of samples are available, which should occur in the next 2 months.

2Compared to the data of the first report (May/21) the most recent findings (June/21) are similar: an almost absolute prevalence of the P.1 variant (Gamma), which still reflects its fast spread in 2021. In May/2021, 605 of the 629 sequenced samples referred to the P.1 variant and in June/2021 the number was higher, 1,277 of the 1,297 were sequenced.

3As anticipated in the first report by Dr. José Eduardo Levi, Genov's lead scientist, the process of local evolution of Gamma (P.1) is evident. It is now possible to notice a small increase in lineages derived from P.1 (P.1.1, P.1.2, etc.), which points to the evolution of the variant.

4Compared to the previous report, in which 12 Gamma-Plus cases were identified from among 489 samples classified as Gamma (12/489= 2.4%), this report analysed an additional 210 Gamma samples from May/21 and 1,232 Gamma sequences from June/2021. This exposed a small increase in the frequency of P.1 samples with mutation in S:P681. The frequency of these variants: S:P681/H/L/R, among the P.1 samples, was of 16/699 (2.3%) in May/21 to 66/1,232 (5.3%) in June/21, which shows an almost twofold increase between the first and the most recent reports.

5The report also looked into data from an outbreak among fully vaccinated health workers. All the healthcare workers had been fully vaccinated against Covid-19 with two doses of CoronaVac in January and February 2021. The investigation concluded that all presented asymptomatic or oligosymptomatic infection (mild symptoms) and that all sequenced samples were identified as the same strain of Gamma variant, however, it did not identify new mutations in the S gene that could justify vaccine escape.

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To read the 2st Genov Report in full, click here

Read all reports click here